A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022

We estimated interim influenza A vaccine effectiveness (VE) following a late sharp rise in cases during an influenza A(H3N2)-dominated 2021/22 season, after lifting COVID-19 restrictions. In children aged 2–6 years offered a live attenuated influenza vaccine, adjusted VE was 62.7% (95% CI: 10.9–84.4...

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Autores principales: Emborg, Hanne-Dorthe, Vestergaard, Lasse S, Botnen, Amanda Bolt, Nielsen, Jens, Krause, Tyra G, Trebbien, Ramona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012088/
https://www.ncbi.nlm.nih.gov/pubmed/35426361
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.15.2200278
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author Emborg, Hanne-Dorthe
Vestergaard, Lasse S
Botnen, Amanda Bolt
Nielsen, Jens
Krause, Tyra G
Trebbien, Ramona
author_facet Emborg, Hanne-Dorthe
Vestergaard, Lasse S
Botnen, Amanda Bolt
Nielsen, Jens
Krause, Tyra G
Trebbien, Ramona
author_sort Emborg, Hanne-Dorthe
collection PubMed
description We estimated interim influenza A vaccine effectiveness (VE) following a late sharp rise in cases during an influenza A(H3N2)-dominated 2021/22 season, after lifting COVID-19 restrictions. In children aged 2–6 years offered a live attenuated influenza vaccine, adjusted VE was 62.7% (95% CI: 10.9–84.4) in hospitalised and 64.2% (95% CI: 50.5–74.1) in non-hospitalised children. In non-hospitalised patients aged 7–44 years, VE was 24.8% (95% CI: 12.8–35.2); VE was non-significant in remaining age groups and hospital/non-hospital settings.
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spelling pubmed-90120882022-05-03 A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022 Emborg, Hanne-Dorthe Vestergaard, Lasse S Botnen, Amanda Bolt Nielsen, Jens Krause, Tyra G Trebbien, Ramona Euro Surveill Rapid Communication We estimated interim influenza A vaccine effectiveness (VE) following a late sharp rise in cases during an influenza A(H3N2)-dominated 2021/22 season, after lifting COVID-19 restrictions. In children aged 2–6 years offered a live attenuated influenza vaccine, adjusted VE was 62.7% (95% CI: 10.9–84.4) in hospitalised and 64.2% (95% CI: 50.5–74.1) in non-hospitalised children. In non-hospitalised patients aged 7–44 years, VE was 24.8% (95% CI: 12.8–35.2); VE was non-significant in remaining age groups and hospital/non-hospital settings. European Centre for Disease Prevention and Control (ECDC) 2022-04-14 /pmc/articles/PMC9012088/ /pubmed/35426361 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.15.2200278 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Emborg, Hanne-Dorthe
Vestergaard, Lasse S
Botnen, Amanda Bolt
Nielsen, Jens
Krause, Tyra G
Trebbien, Ramona
A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022
title A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022
title_full A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022
title_fullStr A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022
title_full_unstemmed A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022
title_short A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022
title_sort late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating a(h3n2) strain, denmark, 2021/22 influenza season up to 25 march 2022
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012088/
https://www.ncbi.nlm.nih.gov/pubmed/35426361
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.15.2200278
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