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SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration

SARM1 (sterile alpha and armadillo motif-containing protein) is a highly conserved Toll/IL-1 Receptor (TIR) adaptor with important roles in mediating immune responses. Studies in the brain have shown that SARM1 plays a role in induction of neuronal axon degeneration in response to a variety of injur...

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Detalles Bibliográficos
Autores principales: Gibbons, Luke, Ozaki, Ema, Greene, Chris, Trappe, Anne, Carty, Michael, Coppinger, Judith A., Bowie, Andrew G., Campbell, Matthew, Doyle, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012108/
https://www.ncbi.nlm.nih.gov/pubmed/35431772
http://dx.doi.org/10.3389/fnins.2022.852114