Cargando…

Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress

BACKGROUND: We assessed whether ICT can alleviate 6-OHDA-induced cell damage via inhibition of oxidative stress by evaluating the protective effect of icaritin (ICT) against 6-hydroxydopamine (6-OHDA)-induced MN9D cell damage and further determined the mechanism by which ICT reduces oxidative stress...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Xinyu, Huang, Nanqu, Hou, Xiaoyi, Zhu, Li, Xie, Yiman, Ba, Zhisheng, Luo, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012182/ https://www.ncbi.nlm.nih.gov/pubmed/35433120 http://dx.doi.org/10.7717/peerj.13256

Ejemplares similares

Icaritin protects SH-SY5Y cells transfected with TDP-43 by alleviating mitochondrial damage and oxidative stress
por: Zhou, Yongjian, et al.
Publicado: (2021)

Effect of icaritin on autophagy-related protein expression in TDP-43-transfected SH-SY5Y cells
por: Zhou, Yanjun, et al.
Publicado: (2022)

Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway
por: Feng, Fei, et al.
Publicado: (2019)

UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion
por: Tang, Yunfeng, et al.
Publicado: (2023)

Resveratrol against 6-OHDA-induced damage of PC12 cells via PI3K/Akt
por: Huang, Nanqu, et al.
Publicado: (2021)

Icariin protects against sodium azide—induced neurotoxicity by activating the PI3K/Akt/GSK-3β signaling pathway
por: Zhang, Ying, et al.
Publicado: (2020)

Sevoflurane preconditioning attenuates hypoxia/reoxygenation injury of H9c2 cardiomyocytes by activation of the HIF-1/PDK-1 pathway
por: Hou, Tianliang, et al.
Publicado: (2020)

Structural insights into the light-driven auto-assembly process of the water-oxidizing Mn(4)CaO(5)-cluster in photosystem II
por: Zhang, Miao, et al.
Publicado: (2017)

Icaritin Provides Neuroprotection in Parkinson’s Disease by Attenuating Neuroinflammation, Oxidative Stress, and Energy Deficiency
por: Wu, Hao, et al.
Publicado: (2021)

Tanshinone ΙΙA-Incubated Mesenchymal Stem Cells Inhibit Lipopolysaccharide-Induced Inflammation of N9 Cells through TREM2 Signaling Pathway
por: Huang, Nanqu, et al.
Publicado: (2022)

CTRP3 attenuates inflammation, oxidative and cell death in cisplatin induced HK-2 cells
por: Zou, Chenglin, et al.
Publicado: (2023)

Relative telomere length and oxidative DNA damage in hypertrophic ligamentum flavum of lumbar spinal stenosis
por: Dechsupa, Sinsuda, et al.
Publicado: (2018)

Protective effects of the extracts of Barringtonia racemosa shoots against oxidative damage in HepG2 cells
por: Kong, Kin Weng, et al.
Publicado: (2016)

A comparative study on the in vitro and in vivo antitumor efficacy of icaritin and hydrous icaritin nanorods
por: Li, Haowen, et al.
Publicado: (2020)

Effect of prolactin on cytotoxicity and oxidative stress in ovine ovarian granulosa cells
por: Yang, Ruochen, et al.
Publicado: (2023)

Sliding to the rescue of damaged DNA
por: Gibb, Bryan, et al.
Publicado: (2012)

Oxidative DNA damage triggers ProNGF-Mediated apoptosis in the striatum of 6-OHDA-treated rats
por: Wang, Tao, et al.
Publicado: (2012)

Naringenin attenuates inflammation and apoptosis of osteoarthritic chondrocytes via the TLR4/TRAF6/NF-κB pathway
por: Wang, Yan, et al.
Publicado: (2023)

Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK
por: Wu, Yue, et al.
Publicado: (2021)

Hemin attenuates response of primary rat adipocytes to adrenergic stimulation
por: Szkudelski, Tomasz, et al.
Publicado: (2021)

Histone H3K9 demethylase JMJD2B/KDM4B promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells by regulating H3K9me2 on RUNX2
por: Kang, Pan, et al.
Publicado: (2022)

AAA+ proteases: the first line of defense against mitochondrial damage
por: Pareek, Gautam
Publicado: (2022)

The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition
por: Hou, Li, et al.
Publicado: (2017)

Cloning, localization and focus formation at DNA damage sites of canine XLF
por: KOIKE, Manabu, et al.
Publicado: (2016)

N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats
por: Pan, Yitong, et al.
Publicado: (2021)

Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis
por: Tian, Huibin, et al.
Publicado: (2022)

Decreased S100A9 expression alleviates Clostridium perfringens beta2 toxin-induced inflammatory injury in IPEC-J2 cells
por: Li, Jie, et al.
Publicado: (2023)

Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism
por: Lu, Huasong, et al.
Publicado: (2015)

Cloning, localization and focus formation at DNA damage sites of canine XRCC4
por: KOIKE, Manabu, et al.
Publicado: (2016)

Cloning, localization and focus formation at DNA damage sites of canine Ku70
por: KOIKE, Manabu, et al.
Publicado: (2017)

Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease
por: Rees, Daniel, et al.
Publicado: (2022)

Correction: Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism
por: Lu, Huasong, et al.
Publicado: (2015)

Identification of MOS9 as an interaction partner for chalcone synthase in the nucleus
por: Watkinson, Jonathan I., et al.
Publicado: (2018)

Nucleosome breathing and remodeling constrain CRISPR-Cas9 function
por: Isaac, R Stefan, et al.
Publicado: (2016)

Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation
por: Avanesov, Andrei S, et al.
Publicado: (2014)

N-acetylcysteine alleviates PCB52-induced hepatotoxicity by repressing oxidative stress and inflammatory responses
por: Zhou, Wen-Tao, et al.
Publicado: (2020)

Effects of 3021 meal replacement powder protect NAFLD via suppressing the ERS, oxidative stress and inflammatory responses
por: Xie, Qi, et al.
Publicado: (2023)

Luteolin attenuates doxorubicin-induced cardiotoxicity by modulating the PHLPP1/AKT/Bcl-2 signalling pathway
por: Zhang, YanDong, et al.
Publicado: (2020)

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization
por: Papp, Stephanie J, et al.
Publicado: (2015)

Low temperature upregulating HSP70 expression to mitigate the paclitaxel-induced damages in NHEK cell
por: Chen, Liang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7cvtahe9kjk90t7ojnjdujduu5