Upregulated YB-1 protein promotes glioblastoma growth through a YB-1/CCT4/mLST8/mTOR pathway

Y-box–binding protein 1 (YB-1) is a multifunctional RNA binding protein involved in virtually every step of RNA metabolism. However, the functions and mechanisms of YB-1 in one of the most aggressive cancers, glioblastoma, are not well understood. In this study, we found that YB-1 protein was marked...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jin-Zhu, Zhu, Hong, You, Pu, Liu, Hui, Wang, Wei-Kang, Fan, Xiaojuan, Yang, Yun, Xu, Keren, Zhu, Yingfeng, Li, Qunyi, Wu, Ping, Peng, Chao, Wong, Catherine C.L., Li, Kaicheng, Shi, Yufeng, Zhang, Nu, Wang, Xiuxing, Zeng, Rong, Huang, Ying, Yang, Liusong, Wang, Zefeng, Hui, Jingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012288/
https://www.ncbi.nlm.nih.gov/pubmed/35239512
http://dx.doi.org/10.1172/JCI146536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012288/
https://www.ncbi.nlm.nih.gov/pubmed/35239512
http://dx.doi.org/10.1172/JCI146536

Ejemplares similares