Aging, VO(2) max, entropy, and COVID-19

The decline in human performance with age at 5000 m, an athletic event requiring high VO(2) max, is remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and men show an identical age-related decline, up to ~100 years old. The precision of the decline shows...

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Detalles Bibliográficos
Autores principales: Spedding, Michael, Marvaud, Robin, Marck, Adrien, Delarochelambert, Quentin, Toussaint, Jean Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012415/
https://www.ncbi.nlm.nih.gov/pubmed/35343209
http://dx.doi.org/10.4103/ijp.ijp_442_21
Descripción
Sumario:The decline in human performance with age at 5000 m, an athletic event requiring high VO(2) max, is remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and men show an identical age-related decline, up to ~100 years old. The precision of the decline shows the limitations for therapy of aging. Mortality incidence for COVID-19 shows a similar relationship. We propose that initial VO(2) max has a critical role in COVID sensitivity because of the direct relationship of disease severity with oxygen use, and the parallel decline in aging.

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