Aging, VO(2) max, entropy, and COVID-19

The decline in human performance with age at 5000 m, an athletic event requiring high VO(2) max, is remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and men show an identical age-related decline, up to ~100 years old. The precision of the decline shows...

Descripción completa

Detalles Bibliográficos
Autores principales: Spedding, Michael, Marvaud, Robin, Marck, Adrien, Delarochelambert, Quentin, Toussaint, Jean Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012415/
https://www.ncbi.nlm.nih.gov/pubmed/35343209
http://dx.doi.org/10.4103/ijp.ijp_442_21
_version_ 1784687791370665984
author Spedding, Michael
Marvaud, Robin
Marck, Adrien
Delarochelambert, Quentin
Toussaint, Jean Francois
author_facet Spedding, Michael
Marvaud, Robin
Marck, Adrien
Delarochelambert, Quentin
Toussaint, Jean Francois
author_sort Spedding, Michael
collection PubMed
description The decline in human performance with age at 5000 m, an athletic event requiring high VO(2) max, is remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and men show an identical age-related decline, up to ~100 years old. The precision of the decline shows the limitations for therapy of aging. Mortality incidence for COVID-19 shows a similar relationship. We propose that initial VO(2) max has a critical role in COVID sensitivity because of the direct relationship of disease severity with oxygen use, and the parallel decline in aging.
format Online
Article
Text
id pubmed-9012415
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-90124152022-04-16 Aging, VO(2) max, entropy, and COVID-19 Spedding, Michael Marvaud, Robin Marck, Adrien Delarochelambert, Quentin Toussaint, Jean Francois Indian J Pharmacol Review Article The decline in human performance with age at 5000 m, an athletic event requiring high VO(2) max, is remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and men show an identical age-related decline, up to ~100 years old. The precision of the decline shows the limitations for therapy of aging. Mortality incidence for COVID-19 shows a similar relationship. We propose that initial VO(2) max has a critical role in COVID sensitivity because of the direct relationship of disease severity with oxygen use, and the parallel decline in aging. Wolters Kluwer - Medknow 2022 2022-03-18 /pmc/articles/PMC9012415/ /pubmed/35343209 http://dx.doi.org/10.4103/ijp.ijp_442_21 Text en Copyright: © 2022 Indian Journal of Pharmacology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Spedding, Michael
Marvaud, Robin
Marck, Adrien
Delarochelambert, Quentin
Toussaint, Jean Francois
Aging, VO(2) max, entropy, and COVID-19
title Aging, VO(2) max, entropy, and COVID-19
title_full Aging, VO(2) max, entropy, and COVID-19
title_fullStr Aging, VO(2) max, entropy, and COVID-19
title_full_unstemmed Aging, VO(2) max, entropy, and COVID-19
title_short Aging, VO(2) max, entropy, and COVID-19
title_sort aging, vo(2) max, entropy, and covid-19
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012415/
https://www.ncbi.nlm.nih.gov/pubmed/35343209
http://dx.doi.org/10.4103/ijp.ijp_442_21
work_keys_str_mv AT speddingmichael agingvo2maxentropyandcovid19
AT marvaudrobin agingvo2maxentropyandcovid19
AT marckadrien agingvo2maxentropyandcovid19
AT delarochelambertquentin agingvo2maxentropyandcovid19
AT toussaintjeanfrancois agingvo2maxentropyandcovid19

Ejemplares similares