Cargando…

Neuroprotective effects of linagliptin in a rotenone-induced rat model of Parkinson's disease

The present study investigates the antiParkinsonian activity of dipeptidyl peptidase-4 (DPP-IV) inhibitor, linagliptin. The experimental Parkinson's disease (PD) was induced by administration of rotenone at a dose of 1.5 mg/kg at alternate day subcutaneously for 21 days. Standard drug (levodopa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abhangi, Kinjal V, Patel, Jigneshkumar Ishwarlal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2022
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012419/ https://www.ncbi.nlm.nih.gov/pubmed/35343207 http://dx.doi.org/10.4103/ijp.IJP_384_20

Ejemplares similares

Neuroprotective and therapeutic effects of calcitriol in rotenone-induced Parkinson’s disease rat model
por: Magdy, Alshimaa, et al.
Publicado: (2022)

Imaging and Quantitative Analysis of the Interstitial Space in the Caudate Nucleus in a Rotenone-Induced Rat Model of Parkinson’s Disease Using Tracer-based MRI
por: Lv, Deyong, et al.
Publicado: (2017)

Neuroprotective effects of Danshensu on rotenone-induced Parkinson’s disease models in vitro and in vivo
por: Wang, Tian, et al.
Publicado: (2020)

Neuroprotective effects of curcumin on the cerebellum in a rotenone‐induced Parkinson’s Disease Model
por: Fikry, Heba, et al.
Publicado: (2022)

Neuroprotective potential of ferulic acid in the rotenone model of Parkinson’s disease
por: Ojha, Shreesh, et al.
Publicado: (2015)

Therapeutic and Neuroprotective Effects of Bushen Jianpi Decoction on a Rotenone-Induced Rat Model of Parkinson's Disease
por: Liang, Wei, et al.
Publicado: (2022)

Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease
por: Yuan, Jiawen, et al.
Publicado: (2016)

Curcumin modulation of L-dopa and rasagiline-induced neuroprotection in rotenone model of Parkinson’s disease
por: El-Shamarka, Marwa El-Sayed, et al.
Publicado: (2023)

Neuroprotective Effects of Thymol, a Dietary Monoterpene Against Dopaminergic Neurodegeneration in Rotenone-Induced Rat Model of Parkinson’s Disease
por: Javed, Hayate, et al.
Publicado: (2019)

Neuroprotective Efficacy of a Nanomicellar Complex of Carnosine and Lipoic Acid in a Rat Model of Rotenone-Induced Parkinson’s Disease
por: Kulikova, Olga, et al.
Publicado: (2023)

Neuroprotective Effects of a Standardized Flavonoid Extract from Safflower against a Rotenone-Induced Rat Model of Parkinson’s Disease
por: Ablat, Nuramatjan, et al.
Publicado: (2016)

Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats★
por: Li, Chun, et al.
Publicado: (2012)

Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism
por: Chiu, Ching-Chi, et al.
Publicado: (2014)

Excessive levels of nitric oxide in rat model of Parkinson’s disease induced by rotenone
por: XIONG, ZHONG-KUI, et al.
Publicado: (2015)

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway
por: Singh, Richa, et al.
Publicado: (2023)

Piracetam and vinpocetine ameliorate rotenone-induced Parkinsonism in rats
por: Zaitone, Sawsan A., et al.
Publicado: (2012)

HR LC-MS/MS metabolomic profiling of Yucca aloifolia fruit and the potential neuroprotective effect on rotenone-induced Parkinson’s disease in rats
por: Ali, Dalia E., et al.
Publicado: (2023)

Evidence of Oropharyngeal Dysfunction in Feeding in the Rat Rotenone Model of Parkinson's Disease
por: Gould, François D. H., et al.
Publicado: (2018)

Microglia-dependent neuroprotective effects of 4-octyl itaconate against rotenone-and MPP+-induced neurotoxicity in Parkinson’s disease
por: Xia, Ning, et al.
Publicado: (2023)

Rotenone, Paraquat, and Parkinson’s Disease
por: Tanner, Caroline M., et al.
Publicado: (2011)

Neuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone-Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson's Disease
por: Tamilselvam, Kuppusamy, et al.
Publicado: (2013)

Effect of moxibustion on mTOR-mediated autophagy in rotenone-induced Parkinson's disease model rats
por: Wang, Shu-ju, et al.
Publicado: (2018)

Treadmill exercise alleviates depressive symptoms in rotenone-induced Parkinson disease rats
por: Shin, Mal-Soon, et al.
Publicado: (2017)

The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain
por: Normando, Eduardo Maria, et al.
Publicado: (2016)

Identification of Molecular Network Associated with Neuroprotective Effects of Yashtimadhu (Glycyrrhiza glabra L.) by Quantitative Proteomics of Rotenone-Induced Parkinson’s Disease Model
por: Karthikkeyan, Gayathree, et al.
Publicado: (2020)

The role of autophagy in Parkinson's disease: rotenone-based modeling
por: Xiong, Nian, et al.
Publicado: (2013)

Data on dose-dependent cytotoxicity of rotenone and neuroprotection conferred by Yashtimadhu (Glycyrrhiza glabra L.) in an in vitro Parkinson's disease model
por: Karthikkeyan, Gayathree, et al.
Publicado: (2021)

Neuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone
por: Javed, Hayate, et al.
Publicado: (2016)

Neuroprotective effect of arctigenin against neuroinflammation and oxidative stress induced by rotenone
por: Zhang, Na, et al.
Publicado: (2018)

Involvement of Akt/mTOR in the Neurotoxicity of Rotenone-Induced Parkinson’s Disease Models
por: Zhang, Yu, et al.
Publicado: (2019)

Neuroprotective mechanisms of ε-viniferin in a rotenone-induced cell model of Parkinson's disease: significance of SIRT3-mediated FOXO3 deacetylation
por: Zhang, Shuo, et al.
Publicado: (2020)

The respiratory chain inhibitor rotenone affects peroxisomal dynamics via its microtubule-destabilising activity
por: Passmore, Josiah B., et al.
Publicado: (2017)

Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial Function in a Rotenone-induced Rat Model of Parkinson’s Disease
por: Zhang, Li, et al.
Publicado: (2018)

The neuroprotective effects of the anti-diabetic drug linagliptin against Aβ-induced neurotoxicity
por: Lin, Chih-Li, et al.
Publicado: (2016)

Neuroprotective effects of olanzapine against rotenone-induced toxicity in PC12 cells
por: Xiong, Ya-jie, et al.
Publicado: (2020)

Protection by the NDI1 Gene against Neurodegeneration in a Rotenone Rat Model of Parkinson's Disease
por: Marella, Mathieu, et al.
Publicado: (2008)

The rat rotenone model reproduces the abnormal pattern of central catecholamine metabolism found in Parkinson's disease
por: Landau, Regev, et al.
Publicado: (2022)

Inhibition of Calpain Attenuates Degeneration of Substantia Nigra Neurons in the Rotenone Rat Model of Parkinson’s Disease
por: Zaman, Vandana, et al.
Publicado: (2022)

The Anticonvulsant and Neuroprotective Effects of Walnuts on the Neurons of Rat Brain Cortex
por: Asadi-Shekaari, Majid, et al.
Publicado: (2012)

Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model
por: Zhang, Dongdong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_11qvueeqcla2vk63potir49h9i