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Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses

Background: Interspinous ligament desmotomy (ISLD) has been shown to improve the comfort of horses diagnosed with overriding dorsal spinous processes (DSP), but its effects on spine mobility are unknown. Objective: To objectively quantify the change in mobility of thoracic vertebrae following ISLD u...

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Autores principales: Biedrzycki, Adam Henry, Elane, George Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012442/
https://www.ncbi.nlm.nih.gov/pubmed/35433641
http://dx.doi.org/10.3389/fbioe.2022.817300
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author Biedrzycki, Adam Henry
Elane, George Louis
author_facet Biedrzycki, Adam Henry
Elane, George Louis
author_sort Biedrzycki, Adam Henry
collection PubMed
description Background: Interspinous ligament desmotomy (ISLD) has been shown to improve the comfort of horses diagnosed with overriding dorsal spinous processes (DSP), but its effects on spine mobility are unknown. Objective: To objectively quantify the change in mobility of thoracic vertebrae following ISLD using CT and medical modeling software. Study design: Prospective cadaveric manipulation of seven equine thoracolumbar spines collected from T11-L1. Methods: Spines were collected from T11-L1 with the musculature intact. Flexion and extension phases were achieved with a ratchet device calibrated to 2000N. Bone volume CT scans were performed in resting, flexion, and extension phase preoperatively. Interspinous ligament desmotomy was performed at each intervertebral space (n = 8), and bone volume CT imaging was repeated for each phase. The spinal sections were individually segmented and imported into medical software for kinematic evaluation. T11 of each phase were superimposed, the distance between each dorsal spinous process, the total length of the spine, and the maximal excursion of the first lumbar vertebra along with angular rotational information were recorded. Results: The mean distance between each dorsal spinous process increased by 5.6 ± 4.9 mm, representing a 24 ± 21% increase in mobility following ISLD. L1 dorsoventral excursion increased by 15.3 ± 11.9 mm, craniocaudal motion increased by 6.9 ± 6.5 mm representing a 47 ± 36.5% and 14.5 ± 13.7% increase, respectively. The rotation of L1 about the mediolateral axis increased by 6.5(°) post-ISLD. Conclusion and Clinical Relevance: ISLD increases dorsoventral, craniocaudal, and rotational motion of the equine spine. The computer modeling methodology used here could be used to evaluate multiplanar spinal kinematics between treatments.
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spelling pubmed-90124422022-04-16 Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses Biedrzycki, Adam Henry Elane, George Louis Front Bioeng Biotechnol Bioengineering and Biotechnology Background: Interspinous ligament desmotomy (ISLD) has been shown to improve the comfort of horses diagnosed with overriding dorsal spinous processes (DSP), but its effects on spine mobility are unknown. Objective: To objectively quantify the change in mobility of thoracic vertebrae following ISLD using CT and medical modeling software. Study design: Prospective cadaveric manipulation of seven equine thoracolumbar spines collected from T11-L1. Methods: Spines were collected from T11-L1 with the musculature intact. Flexion and extension phases were achieved with a ratchet device calibrated to 2000N. Bone volume CT scans were performed in resting, flexion, and extension phase preoperatively. Interspinous ligament desmotomy was performed at each intervertebral space (n = 8), and bone volume CT imaging was repeated for each phase. The spinal sections were individually segmented and imported into medical software for kinematic evaluation. T11 of each phase were superimposed, the distance between each dorsal spinous process, the total length of the spine, and the maximal excursion of the first lumbar vertebra along with angular rotational information were recorded. Results: The mean distance between each dorsal spinous process increased by 5.6 ± 4.9 mm, representing a 24 ± 21% increase in mobility following ISLD. L1 dorsoventral excursion increased by 15.3 ± 11.9 mm, craniocaudal motion increased by 6.9 ± 6.5 mm representing a 47 ± 36.5% and 14.5 ± 13.7% increase, respectively. The rotation of L1 about the mediolateral axis increased by 6.5(°) post-ISLD. Conclusion and Clinical Relevance: ISLD increases dorsoventral, craniocaudal, and rotational motion of the equine spine. The computer modeling methodology used here could be used to evaluate multiplanar spinal kinematics between treatments. Frontiers Media S.A. 2022-04-01 /pmc/articles/PMC9012442/ /pubmed/35433641 http://dx.doi.org/10.3389/fbioe.2022.817300 Text en Copyright © 2022 Biedrzycki and Elane. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Biedrzycki, Adam Henry
Elane, George Louis
Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses
title Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses
title_full Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses
title_fullStr Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses
title_full_unstemmed Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses
title_short Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses
title_sort three-dimensional modeling and in silico kinematic evaluation of interspinous ligament desmotomy in horses
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012442/
https://www.ncbi.nlm.nih.gov/pubmed/35433641
http://dx.doi.org/10.3389/fbioe.2022.817300
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