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Frequency-Dependent Competition Between Strains Imparts Persistence to Perturbations in a Model of Plasmodium falciparum Malaria Transmission

In high-transmission endemic regions, local populations of Plasmodium falciparum exhibit vast diversity of the var genes encoding its major surface antigen, with each parasite comprising multiple copies from this diverse gene pool. This strategy to evade the immune system through large combinatorial...

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Detalles Bibliográficos
Autores principales: He, Qixin, Pilosof, Shai, Tiedje, Kathryn E., Day, Karen P., Pascual, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012452/
https://www.ncbi.nlm.nih.gov/pubmed/35433714
http://dx.doi.org/10.3389/fevo.2021.633263