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Frequency-Dependent Competition Between Strains Imparts Persistence to Perturbations in a Model of Plasmodium falciparum Malaria Transmission
In high-transmission endemic regions, local populations of Plasmodium falciparum exhibit vast diversity of the var genes encoding its major surface antigen, with each parasite comprising multiple copies from this diverse gene pool. This strategy to evade the immune system through large combinatorial...
Autores principales: | He, Qixin, Pilosof, Shai, Tiedje, Kathryn E., Day, Karen P., Pascual, Mercedes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012452/ https://www.ncbi.nlm.nih.gov/pubmed/35433714 http://dx.doi.org/10.3389/fevo.2021.633263 |
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