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Structure of the ciliogenesis-associated CPLANE complex

Dysfunctional cilia cause pleiotropic human diseases termed ciliopathies. These hereditary maladies are often caused by defects in cilia assembly, a complex event that is regulated by the ciliogenesis and planar polarity effector (CPLANE) proteins Wdpcp, Inturned, and Fuzzy. CPLANE proteins are esse...

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Detalles Bibliográficos
Autores principales: Langousis, Gerasimos, Cavadini, Simone, Boegholm, Niels, Lorentzen, Esben, Kempf, Georg, Matthias, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012472/
https://www.ncbi.nlm.nih.gov/pubmed/35427153
http://dx.doi.org/10.1126/sciadv.abn0832