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Progranulin and Its Receptor Predict Kidney Function Decline in Patients With Type 2 Diabetes

Progranulin (PGRN), a growth factor, is abundantly expressed in a broad range of tissues and cell types with pleiotropic functions including inflammation, neurodegeneration, and facilitating lysosome acidification. PGRN binds to TNF receptors (TNFR) and inhibits downstream inflammatory signaling pat...

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Detalles Bibliográficos
Autores principales:	Murakoshi, Maki, Gohda, Tomohito, Sakuma, Hiroko, Shibata, Terumi, Adachi, Eri, Kishida, Chiaki, Ichikawa, Saki, Koshida, Takeo, Kamei, Nozomu, Suzuki, Yusuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012489/ https://www.ncbi.nlm.nih.gov/pubmed/35432201 http://dx.doi.org/10.3389/fendo.2022.849457

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