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Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?

Necrotizing pancreatitis is an inflammatory process that poses a strong risk of systemic venous thromboembolism. However, it is often challenging to opt for systemic anticoagulation since the disease is also associated with an increased risk of hemorrhage. Given these opposing complications, a risk...

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Detalles Bibliográficos
Autores principales: Abi-Saleh, Simon P, Miller, Ethan A, Magge, Anil, Perez, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012552/
https://www.ncbi.nlm.nih.gov/pubmed/35449612
http://dx.doi.org/10.7759/cureus.23267
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author Abi-Saleh, Simon P
Miller, Ethan A
Magge, Anil
Perez, Mario
author_facet Abi-Saleh, Simon P
Miller, Ethan A
Magge, Anil
Perez, Mario
author_sort Abi-Saleh, Simon P
collection PubMed
description Necrotizing pancreatitis is an inflammatory process that poses a strong risk of systemic venous thromboembolism. However, it is often challenging to opt for systemic anticoagulation since the disease is also associated with an increased risk of hemorrhage. Given these opposing complications, a risk versus benefit analysis has to be employed in the management of necrotizing pancreatitis on a case-by-case basis. We discuss a case where the team was faced with a dilemma regarding anticoagulation in a patient with newly developed atrial fibrillation in the setting of necrotizing pancreatitis. We found that there is a lack of guidelines that address the time of initiation and the type of systemic anticoagulation that should be administered in such patients.
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spelling pubmed-90125522022-04-20 Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate? Abi-Saleh, Simon P Miller, Ethan A Magge, Anil Perez, Mario Cureus Gastroenterology Necrotizing pancreatitis is an inflammatory process that poses a strong risk of systemic venous thromboembolism. However, it is often challenging to opt for systemic anticoagulation since the disease is also associated with an increased risk of hemorrhage. Given these opposing complications, a risk versus benefit analysis has to be employed in the management of necrotizing pancreatitis on a case-by-case basis. We discuss a case where the team was faced with a dilemma regarding anticoagulation in a patient with newly developed atrial fibrillation in the setting of necrotizing pancreatitis. We found that there is a lack of guidelines that address the time of initiation and the type of systemic anticoagulation that should be administered in such patients. Cureus 2022-03-17 /pmc/articles/PMC9012552/ /pubmed/35449612 http://dx.doi.org/10.7759/cureus.23267 Text en Copyright © 2022, Abi-Saleh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Abi-Saleh, Simon P
Miller, Ethan A
Magge, Anil
Perez, Mario
Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?
title Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?
title_full Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?
title_fullStr Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?
title_full_unstemmed Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?
title_short Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?
title_sort necrotizing pancreatitis: to anticoagulate or not to anticoagulate?
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012552/
https://www.ncbi.nlm.nih.gov/pubmed/35449612
http://dx.doi.org/10.7759/cureus.23267
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