RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression

Androgen receptor (AR) signaling drives prostate cancer (PC) progression. Androgen deprivation therapy (ADT) is temporally effective, whereas drug resistance inevitably develops. Abnormal expression of AR/ARV7 (the most common AR splicing variant) is critical for endocrine resistance, while the deta...

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Detalles Bibliográficos
Autores principales: Zhou, Tingting, Wang, Shengli, Song, Xiaoyu, Liu, Wensu, Dong, Fang, Huo, Yunlong, Zou, Renlong, Wang, Chunyu, Zhang, Siyi, Liu, Wei, Sun, Ge, Lin, Lin, Zeng, Kai, Dong, Xiang, Guo, Qiqiang, Yi, Fei, Wang, Zhuo, Li, Xiaoman, Jiang, Bo, Cao, Liu, Zhao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012884/
https://www.ncbi.nlm.nih.gov/pubmed/35428760
http://dx.doi.org/10.1038/s41419-022-04787-9

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