Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

ARID2 is the most recurrently mutated SWI/SNF complex member in melanoma; however, its tumor-suppressive mechanisms in the context of the chromatin landscape remain to be elucidated. Here, we model ARID2 deficiency in melanoma cells, which results in defective PBAF complex assembly with a concomitan...

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Detalles Bibliográficos
Autores principales: Carcamo, Saul, Nguyen, Christie B., Grossi, Elena, Filipescu, Dan, Alpsoy, Aktan, Dhiman, Alisha, Sun, Dan, Narang, Sonali, Imig, Jochen, Martin, Tiphaine C., Parsons, Ramon, Aifantis, Iannis, Tsirigos, Aristotelis, Aguirre-Ghiso, Julio A., Dykhuizen, Emily C., Hasson, Dan, Bernstein, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013128/
https://www.ncbi.nlm.nih.gov/pubmed/35385731
http://dx.doi.org/10.1016/j.celrep.2022.110637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013128/
https://www.ncbi.nlm.nih.gov/pubmed/35385731
http://dx.doi.org/10.1016/j.celrep.2022.110637

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