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Overexpression of Aquaporin-3 Alleviates Hyperosmolarity-Induced Nucleus Pulposus Cell Apoptosis via Regulating the ERK1/2 Pathway

Intervertebral disc degeneration (IDD) is closely related to osmolarity, which fluctuates with daily activities, and hyperosmolarity may be a contributor to nucleus pulposus (NP) cells apoptosis. Aquaporin-3 (AQP-3) belongs to the family of aquaporins and mainly transports water and other small mole...

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Detalles Bibliográficos
Autores principales: Zhang, Zetong, Zhao, Chen, Zhang, Ruijie, Wang, Yiyang, Hu, Yanzhu, Zhou, Qiang, Li, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013301/
https://www.ncbi.nlm.nih.gov/pubmed/35437455
http://dx.doi.org/10.1155/2022/1639560