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The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease

Dysregulation of nicotinamide adenine dinucleotide (NAD +) metabolism contributes to the initiation and progression of age-associated diseases, including chronic kidney disease (CKD). Nicotinamide N-methyltransferase (NNMT), a nicotinamide (NAM) metabolizing enzyme, regulates both NAD + and methioni...

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Detalles Bibliográficos
Autores principales:	Takahashi, Rina, Kanda, Takeshi, Komatsu, Motoaki, Itoh, Tomoaki, Minakuchi, Hitoshi, Urai, Hidenori, Kuroita, Tomohiro, Shigaki, Shuhei, Tsukamoto, Tasuku, Higuchi, Naoko, Ikeda, Minoru, Yamanaka, Risa, Yoshimura, Norito, Ono, Takashi, Yukioka, Hideo, Hasegawa, Kazuhiro, Tokuyama, Hirobumi, Wakino, Shu, Itoh, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013399/ https://www.ncbi.nlm.nih.gov/pubmed/35430611 http://dx.doi.org/10.1038/s41598-022-10476-6

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