A path-based analysis of infected cell line and COVID-19 patient transcriptome reveals novel potential targets and drugs against SARS-CoV-2

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Most transcriptomic studies of SARS-CoV-2 infection have focused on differentially expressed genes, which do not necessarily reveal the genes mediating the transcriptomic changes. In contrast, exploiting curated biological network, our PathExt tool identifies central genes from the differentially ac...

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Detalles Bibliográficos
Autores principales: Agrawal, Piyush, Sambaturu, Narmada, Olgun, Gulden, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013431/
https://www.ncbi.nlm.nih.gov/pubmed/35434729
http://dx.doi.org/10.21203/rs.3.rs-1474136/v1

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