Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway

PURPOSE: It is well known that inflammation plays a key role in complex pathological progressions of alcohol-associated liver disease (ALD). To date, effective therapy for ALD is lacking. P2Y2 receptor (P2Y2R), a G protein-coupled P2Y purinergic receptor, represents a novel pharmacological target in...

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Detalles Bibliográficos
Autores principales: Liu, Zhen-Ni, Su, Qian-Qian, Wang, Yu-Hui, Wu, Xue, Lv, Xiong-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013714/
https://www.ncbi.nlm.nih.gov/pubmed/35444406
http://dx.doi.org/10.2147/DDDT.S346376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013714/
https://www.ncbi.nlm.nih.gov/pubmed/35444406
http://dx.doi.org/10.2147/DDDT.S346376

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