c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses

B cells secreting IL-10 functionally are recognized as functional regulatory B (B(reg)) cells; however, direct evidence concerning the phenotype, regulation, and functional and clinical relevance of IL-10-secreting B(reg) cells in humans is still lacking. Here, we demonstrate that, although IL-10 it...

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Detalles Bibliográficos
Autores principales: Wang, Xu-Yan, Wei, Yuan, Hu, Bo, Liao, Yuan, Wang, Xiaodong, Wan, Wen-Hua, Huang, Chun-Xiang, Mahabati, Mahepali, Liu, Zheng-Yu, Qu, Jing-Rui, Chen, Xiao-Dan, Chen, Dong-Ping, Kuang, Dong-Ming, Wang, Xue-Hao, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013717/
https://www.ncbi.nlm.nih.gov/pubmed/35430810
http://dx.doi.org/10.1038/s41392-022-00948-6

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