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Synthetic Circular gRNA Mediated Biological Function of CRISPR-(d)Cas9 System
Ever since the gene editing function was discovered in the CRISPR-Cas9 system, numerous applications and utilities were investigated in order to apply this technique to medical use. However, the clinical practice was limited by unsatisfactory efficiency and unacceptable off-target editing. Modificat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013764/ https://www.ncbi.nlm.nih.gov/pubmed/35445012 http://dx.doi.org/10.3389/fcell.2022.863431 |