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Contractile State Dependent Sarcomere Length Variability in Isolated Guinea-Pig Cardiomyocytes

Cardiomyocytes contract keeping their sarcomere length (SL) close to optimal values for force generation. Transmural heterogeneity in SL across the ventricular wall coordinates the contractility of the whole-ventricle. SL heterogeneity (variability) exists not only at the tissue (macroscale) level,...

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Detalles Bibliográficos
Autores principales: Lookin, Oleg, Khokhlova, Anastasia, Myachina, Tatiana, Butova, Xenia, Cazorla, Olivier, de Tombe, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013801/
https://www.ncbi.nlm.nih.gov/pubmed/35444559
http://dx.doi.org/10.3389/fphys.2022.857471