Notch-Signaling Deregulation Induces Myeloid-Derived Suppressor Cells in T-Cell Acute Lymphoblastic Leukemia

Notch receptors deeply influence T-cell development and differentiation, and their dysregulation represents a frequent causative event in “T-cell acute lymphoblastic leukemia” (T-ALL). “Myeloid-derived suppressor cells” (MDSCs) inhibit host immune responses in the tumor environment, favoring cancer...

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Detalles Bibliográficos
Autores principales: Grazioli, Paola, Orlando, Andrea, Giordano, Nike, Noce, Claudia, Peruzzi, Giovanna, Abdollahzadeh, Behnaz, Screpanti, Isabella, Campese, Antonio Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013886/
https://www.ncbi.nlm.nih.gov/pubmed/35444651
http://dx.doi.org/10.3389/fimmu.2022.809261

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