Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients

INTRODUCTION: Regulatory T cell (Treg) therapy has been demonstrated to facilitate long-term allograft survival in preclinical models of transplantation and may permit reduction of immunosuppression and its associated complications in the clinical setting. Phase 1 clinical trials have shown Treg the...

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Detalles Bibliográficos
Autores principales: Brook, Matthew Oliver, Hester, Joanna, Petchey, William, Rombach, Ines, Dutton, Susan, Bottomley, Matthew James, Black, Joanna, Abdul-Wahab, Seetha, Bushell, Andrew, Lombardi, Giovanna, Wood, Kathryn, Friend, Peter, Harden, Paul, Issa, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Renal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014059/
https://www.ncbi.nlm.nih.gov/pubmed/35428650
http://dx.doi.org/10.1136/bmjopen-2022-061864

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