Cargando…

Extraction Optimization, Structural Characterization, and Anti-Hepatoma Activity of Acidic Polysaccharides From Scutellaria barbata D. Don

The Chinese medicinal herb Scutellaria barbata D. Don has antitumour effects and is used to treat liver cancer in the clinic. S. barbata polysaccharide (SBP), one of the main active components extracted from S. barbata D. Don, exhibits antitumour activity. However, there is still a lack of research...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Wenwen, Wu, Leilei, Liang, Qichao, Lin, Xiaoyue, Xu, Xiaoyi, Yu, Shikai, Lin, Yitong, Zhou, Jiadong, Fu, Yang, Gao, Xiaoyan, Zhang, Bo, Li, Li, Li, Dan, Yin, Yongkui, Song, Gaochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014130/ https://www.ncbi.nlm.nih.gov/pubmed/35444545 http://dx.doi.org/10.3389/fphar.2022.827782

Ejemplares similares

Scutellaria barbata polysaccharides inhibit tumor growth and affect the serum proteomic profiling of hepatoma H22-bearing mice
por: Li, Li, et al.
Publicado: (2019)

The complete chloroplast genome of Scutellaria barbata D. Don 1825 revealed the phylogenetic relationships of the Scutellaria genus
por: Pan, Shouhui, et al.
Publicado: (2023)

Anti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

A Novel Systems Pharmacology Method to Investigate Molecular Mechanisms of Scutellaria barbata D. Don for Non-small Cell Lung Cancer
por: Liu, Jianling, et al.
Publicado: (2018)

Scutellaria barbata D. Don Polysaccharides Inhibit High Glucose-Induced Proliferation and Angiogenesis of Retinal Vascular Endothelial Cells
por: Li, Wenjun, et al.
Publicado: (2021)

Study on the mechanism of action of Scutellaria barbata on hepatocellular carcinoma based on network pharmacology and bioinformatics
por: Yang, An-Yin, et al.
Publicado: (2023)

Two New Phenols from Scutellaria barbata
por: Wang, Gang, et al.
Publicado: (2011)

Functional components in Scutellaria barbata D. Don with anti-inflammatory activity on RAW 264.7 cells
por: Liu, Hsin-Lan, et al.
Publicado: (2017)

Antitumor Effects and the Compatibility Mechanisms of Herb Pair Scleromitrion diffusum (Willd.) R. J. Wang–Sculellaria barbata D. Don
por: Lu, Li, et al.
Publicado: (2020)

The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells
por: Chen, Chin-Chuan, et al.
Publicado: (2017)

Molecular Assessment of Scutellaria barbata D. Don in the Treatment of Nasopharyngeal Carcinoma Based on Network Pharmacology and Experimental Verification
por: Shi, Hongjian, et al.
Publicado: (2022)

Scutellaria barbata D. Don Inhibits Tumor Angiogenesis via Suppression of Hedgehog Pathway in a Mouse Model of Colorectal Cancer
por: Wei, Lihui, et al.
Publicado: (2012)

Network pharmacology-based strategy to investigate the active ingredients and molecular mechanisms of Scutellaria Barbata D. Don against radiation pneumonitis
por: Sun, Ping-Yi, et al.
Publicado: (2021)

Comparative Genome Analysis of Scutellaria baicalensis and Scutellaria barbata Reveals the Evolution of Active Flavonoid Biosynthesis
por: Xu, Zhichao, et al.
Publicado: (2020)

Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice
por: Gong, Tao, et al.
Publicado: (2015)

Identification of Flavonoids from Scutellaria barbata D. Don as Inhibitors of HIV-1 and Cathepsin L Proteases and Their Structure–Activity Relationships
por: Tang, Ting-Ting, et al.
Publicado: (2023)

Scutellaria barbata D. Don extract inhibits the tumor growth through down-regulating of Treg cells and manipulating Th1/Th17 immune response in hepatoma H22-bearing mice
por: Kan, Xuefeng, et al.
Publicado: (2017)

Scutellaria barbata Inhibits Hepatocellular Carcinoma Tumorigenicity by Inducing Ferroptosis of Hepatocellular Carcinoma Cells
por: Li, Yue, et al.
Publicado: (2022)

Total Flavonoids of Scutellaria barbata Inhibit Invasion of Hepatocarcinoma via MMP/TIMP in Vitro
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

Investigating the Mechanism of Scutellariae barbata Herba in the Treatment of Colorectal Cancer by Network Pharmacology and Molecular Docking
por: Qi, Xiangjun, et al.
Publicado: (2021)

Systematic Investigation of Scutellariae Barbatae Herba for Treating Hepatocellular Carcinoma Based on Network Pharmacology
por: Gong, Benjiao, et al.
Publicado: (2018)

Transcriptomic Insight into Terpenoid Biosynthesis and Functional Characterization of Three Diterpene Synthases in Scutellaria barbata
por: Zhang, Huabei, et al.
Publicado: (2018)

Using the Chinese herb Scutellaria barbata against extensively drug-resistant Acinetobacter baumannii infections: in vitro and in vivo studies
por: Tsai, Chin-Chuan, et al.
Publicado: (2018)

Inductions of Caspase-, MAPK- and ROS-dependent Apoptosis and Chemotherapeutic Effects Caused by an Ethanol Extract of Scutellaria barbata D. Don in Human Gastric Adenocarcinom Cells
por: Shim, Ji Hwan, et al.
Publicado: (2016)

Inhibition effects of total flavonoids from Scutellaria barbata D. Don on human breast carcinoma bone metastasis via downregulating PTHrP pathway
por: Zheng, Xiao, et al.
Publicado: (2018)

Scutellaria barbata D.Don (SBD) extracts suppressed tumor growth, metastasis and angiogenesis in Prostate cancer via PI3K/Akt pathway
por: Sheng, Dongya, et al.
Publicado: (2022)

Scutellaria barbata D. Don Inhibits the Main Proteases (M(pro) and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
por: Huang, Sheng-Teng, et al.
Publicado: (2021)

Anti-Photoaging Activity of Scutellaria barbata D. Don (Family Lamiaceae) on Ultraviolet B-Irradiated NIH-3T3 Skin Fibroblast and SKH-1 Hairless Mouse
por: Jung, Jong Min, et al.
Publicado: (2022)

Scutellaria barbata flavonoids alleviate memory deficits and neuronal injuries induced by composited Aβ in rats
por: Wu, Xiao G., et al.
Publicado: (2016)

AURKB, CHEK1 and NEK2 as the Potential Target Proteins of Scutellaria barbata on Hepatocellular Carcinoma: An Integrated Bioinformatics Analysis
por: Huang, Chaoyuan, et al.
Publicado: (2021)

Hedyotis diffusa Combined with Scutellaria barbata Are the Core Treatment of Chinese Herbal Medicine Used for Breast Cancer Patients: A Population-Based Study
por: Yeh, Yuan-Chieh, et al.
Publicado: (2014)

Ganoderma Lucidum Polysaccharides Enhance the Abscopal Effect of Photothermal Therapy in Hepatoma-Bearing Mice Through Immunomodulatory, Anti-Proliferative, Pro-Apoptotic and Anti-Angiogenic
por: Xia, Qing-Hai, et al.
Publicado: (2021)

Molecular Targets and Mechanisms of Hedyotis diffusa-Scutellaria barbata Herb Pair for the Treatment of Colorectal Cancer Based on Network Pharmacology and Molecular Docking
por: Yang, Zhenpeng, et al.
Publicado: (2022)

Stepwise Diagnostic Product Ions Filtering Strategy for Rapid Discovery of Diterpenoids in Scutellaria barbata Based on UHPLC-Q-Exactive-Orbitrap-MS
por: Zhou, Xinhua, et al.
Publicado: (2022)

The Function of Natural Polysaccharides in the Treatment of Ulcerative Colitis
por: Guo, Yafei, et al.
Publicado: (2022)

The Medicinal Plant Pair Bupleurum chinense-Scutellaria baicalensis – Metabolomics and Metallomics Analysis in a Model for Alcoholic Liver Injury
por: Dang, Zefang, et al.
Publicado: (2019)

The Key Target and Molecular Mechanism of the Volatile Component of Scutellaria baicalensis Georgi in Acute Lung Injury Based on Network Pharmacology
por: Zhu, Guosong, et al.
Publicado: (2021)

Hedyotis diffusa plus Scutellaria barbata Induce Bladder Cancer Cell Apoptosis by Inhibiting Akt Signaling Pathway through Downregulating miR-155 Expression
por: Pan, Li-Tao, et al.
Publicado: (2016)

The Codelivery of siRNA and QDs by pH-Responsive Micelle for Hepatoma Cancer Cells
por: Cao, Zhonglin, et al.
Publicado: (2019)

Scutellaria baicalensis georgi is a promising candidate for the treatment of autoimmune diseases
por: Wang, Jun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_be3aintpcadh9mq0irp4f7hfdt