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Diagnostic Potential of Plasma IgA1 O-Glycans in Discriminating IgA Nephropathy From Other Glomerular Diseases and Healthy Participants

Background: Aberrant O-glycosylation of IgA1 plays an important role in IgA nephropathy pathogenesis. Previous proteomic studies analyzed O-glycans of the circulating IgA1 hinge region and found that the N-acetylgalactosamine (GalNAc) and galactose numbers in the hinge region of IgA1 of patients wit...

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Detalles Bibliográficos
Autores principales: Zhang, Shuyu, Sun, Haidan, Zhang, Zejian, Li, Menglin, Guo, Zhengguang, Ye, Wenling, Cai, Guangyan, Sun, Wei, Li, Mingxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014244/
https://www.ncbi.nlm.nih.gov/pubmed/35445079
http://dx.doi.org/10.3389/fmolb.2022.871615

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