Cargando…

AIOLOS Variants Causing Immunodeficiency in Human and Mice

AIOLOS is encoded by IKZF3 and is a member of the IKAROS zinc finger transcription factor family. Heterozygous missense variants in the second zinc finger of AIOLOS have recently been reported to be found in the families of patients with inborn errors of immunity. The AIOLOS(G159R) variant was ident...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamashita, Motoi, Morio, Tomohiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014263/ https://www.ncbi.nlm.nih.gov/pubmed/35444653 http://dx.doi.org/10.3389/fimmu.2022.866582

Ejemplares similares

T and B cell abnormalities, pneumocystis pneumonia, and chronic lymphocytic leukemia associated with an AIOLOS defect in patients
por: Kuehn, Hye Sun, et al.
Publicado: (2021)

Aiolos and Lymphocyte Mimicry in Lung Cancer
por: Terada, Lance S, et al.
Publicado: (2014)

Aiolos regulates eosinophil migration into tissues
por: Felton, Jennifer M., et al.
Publicado: (2021)

Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus
por: Rivellese, Felice, et al.
Publicado: (2021)

Combined immunodeficiency caused by pathogenic variants in the ZAP70 C-terminal SH2 domain
por: Mongellaz, Cédric, et al.
Publicado: (2023)

Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL
por: Hagner, Patrick R., et al.
Publicado: (2022)

IKZF3/Aiolos Is Associated with but Not Sufficient for the Expression of IL-10 by CD4(+) T Cells
por: Ridley, Michael L., et al.
Publicado: (2020)

Tissue signals imprint Aiolos expression in ILC2s to modulate type 2 immunity
por: Qiu, Jinxin, et al.
Publicado: (2021)

The development and improvement of immunodeficient mice and humanized immune system mouse models
por: Chen, Jiaxuan, et al.
Publicado: (2022)

A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage
por: Fliegauf, Manfred, et al.
Publicado: (2021)

Case Report: Rotavirus Vaccination and Severe Combined Immunodeficiency in Japan
por: Tanita, Kay, et al.
Publicado: (2022)

Impaired tissue homing by the Ikzf3(N159S) variant is mediated by interfering with Ikaros function
por: Chang, Jingjie, et al.
Publicado: (2023)

Molecular and anatomical roadmap of stroke pathology in immunodeficient mice
por: Weber, Rebecca Z., et al.
Publicado: (2022)

Human Immune System Mice for the Study of Human Immunodeficiency Virus-Type 1 Infection of the Central Nervous System
por: Evering, Teresa H., et al.
Publicado: (2018)

Aiolos Is Required for the Generation of High Affinity Bone Marrow Plasma Cells Responsible for Long-Term Immunity
por: Cortés, Marta, et al.
Publicado: (2004)

Genetic Mapping and Allelic Loss Analysis in Mouse Thymic Lymphomas of Helios and Aiolos Belonging to the Ikaros Gene Family
por: Xu, Hongbin, et al.
Publicado: (2001)

Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells
por: Hung, Jung-Jyh, et al.
Publicado: (2019)

Inborn errors of immunity—recent advances in research on the pathogenesis
por: Yamashita, Motoi, et al.
Publicado: (2021)

Case report: HLA-haploidentical hematopoietic cell transplant with posttransplant cyclophosphamide in a patient with leukocyte adhesion deficiency type I
por: Yamashita, Motoi, et al.
Publicado: (2022)

Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in NFKB1
por: Anim, Manfred, et al.
Publicado: (2021)

Human Immunodeficiencies Related to Defective APC/T Cell Interaction
por: Kallikourdis, Marinos, et al.
Publicado: (2015)

γδ T Lymphocytes in the Diagnosis of Human T Cell Receptor Immunodeficiencies
por: Garcillán, Beatriz, et al.
Publicado: (2015)

Silencing and Nuclear Repositioning of the λ5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1
por: Karnowski, Alexander, et al.
Publicado: (2008)

Role of Aiolos and Ikaros in the Antitumor and Immunomodulatory Activity of IMiDs in Multiple Myeloma: Better to Lose Than to Find Them
por: Cippitelli, Marco, et al.
Publicado: (2021)

CCR5 as a Coreceptor for Human Immunodeficiency Virus and Simian Immunodeficiency Viruses: A Prototypic Love-Hate Affair
por: Jasinska, Anna J., et al.
Publicado: (2022)

Gastric Cancer Is the Leading Cause of Death in Italian Adult Patients With Common Variable Immunodeficiency
por: Pulvirenti, Federica, et al.
Publicado: (2018)

Hemizygous nonsense variant in the moesin gene (MSN) leads to a new autoimmune phenotype of Immunodeficiency 50
por: Kovács, András L., et al.
Publicado: (2022)

Corrigendum: Vulnerability to meningococcal disease in immunodeficiency due to a novel pathogenic missense variant in NFKB1
por: Anim, Manfred, et al.
Publicado: (2023)

Follicular Dendritic Cells of Lymph Nodes as Human Immunodeficiency Virus/Simian Immunodeficiency Virus Reservoirs and Insights on Cervical Lymph Node
por: Dave, Rajnish S., et al.
Publicado: (2018)

Human Immunodeficiency Syndromes Affecting Human Natural Killer Cell Cytolytic Activity
por: Ham, Hyoungjun, et al.
Publicado: (2014)

Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model
por: Kim, Jiae, et al.
Publicado: (2017)

Strategies for B-Cell Receptor Repertoire Analysis in Primary Immunodeficiencies: From Severe Combined Immunodeficiency to Common Variable Immunodeficiency
por: IJspeert, Hanna, et al.
Publicado: (2015)

Cereblon modulator iberdomide induces degradation of the transcription factors Ikaros and Aiolos: immunomodulation in healthy volunteers and relevance to systemic lupus erythematosus
por: Schafer, Peter H, et al.
Publicado: (2018)

Author Correction: Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells
por: Hung, Jung-Jyh, et al.
Publicado: (2020)

Aiolos represses CD4(+) T cell cytotoxic programming via reciprocal regulation of T(FH) transcription factors and IL-2 sensitivity
por: Read, Kaitlin A., et al.
Publicado: (2023)

Sepsis causes neutrophil infiltration in muscle leading to muscle atrophy and weakness in mice
por: Nakanishi, Nobuto, et al.
Publicado: (2022)

Endocrinopathies in Inborn Errors of Immunity
por: Takasawa, Kei, et al.
Publicado: (2021)

Human Immunodeficiency Virus and Heparan Sulfate: From Attachment to Entry Inhibition
por: Connell, Bridgette J., et al.
Publicado: (2013)

Novel Primary Immunodeficiency Candidate Genes Predicted by the Human Gene Connectome
por: Itan, Yuval, et al.
Publicado: (2015)

Chemokines and Chemokine Receptors: Accomplices for Human Immunodeficiency Virus Infection and Latency
por: Wang, Zhuo, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bmk2p8rruvtnu4b9adofq5fefc