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A Rapid Assessment Model for Liver Toxicity of Macrolides and an Integrative Evaluation for Azithromycin Impurities

Impurities in pharmaceuticals of potentially hazardous materials may cause drug safety problems. Macrolide antibiotic preparations include active pharmaceutical ingredients (APIs) and different types of impurities with similar structures, and the amount of these impurities is usually very low and di...

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Detalles Bibliográficos
Autores principales: Zhang, Miao-Qing, Zhang, Jing-Pu, Hu, Chang-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014295/
https://www.ncbi.nlm.nih.gov/pubmed/35444552
http://dx.doi.org/10.3389/fphar.2022.860702