Molecular Patho-mechanisms of cervical cancer (MMP1)

Cervical cancer mostly caused by Human Papilloma Virus. Staging and therapy have been extensively studied, and highly correlated with the cellular development of oncogenesis. Mutation was caused by E6 and E7 oncoprotein, also inactivation of 2 tumor suppressor factors (pRB and p53). P53 also regulat...

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Autores principales: Kurnia, Iwan, Rauf, Syahrul, Hatta, Mochammad, Arifuddin, Sharvianty, Hidayat, Yudi Maulana, Natzir, Rosdiana, Kaelan, Cahyo, Bukhari, Agussalim, Pelupessy, Nugraha Utama, Patelonggi, Ilham Jaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Systematic Review / Meta-analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014365/
https://www.ncbi.nlm.nih.gov/pubmed/35444805
http://dx.doi.org/10.1016/j.amsu.2022.103415
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author Kurnia, Iwan
Rauf, Syahrul
Hatta, Mochammad
Arifuddin, Sharvianty
Hidayat, Yudi Maulana
Natzir, Rosdiana
Kaelan, Cahyo
Bukhari, Agussalim
Pelupessy, Nugraha Utama
Patelonggi, Ilham Jaya
author_facet Kurnia, Iwan
Rauf, Syahrul
Hatta, Mochammad
Arifuddin, Sharvianty
Hidayat, Yudi Maulana
Natzir, Rosdiana
Kaelan, Cahyo
Bukhari, Agussalim
Pelupessy, Nugraha Utama
Patelonggi, Ilham Jaya
author_sort Kurnia, Iwan
collection PubMed
description Cervical cancer mostly caused by Human Papilloma Virus. Staging and therapy have been extensively studied, and highly correlated with the cellular development of oncogenesis. Mutation was caused by E6 and E7 oncoprotein, also inactivation of 2 tumor suppressor factors (pRB and p53). P53 also regulated MMP1, which dysregulation of MMP transcription would promote tumor metastasis, because of its role in extracellular matrix degradation in tumor invasion. Clinical staging of Cervical Cancer was based on Federation International of Gynaecology and Obstetrics (FIGO) classification from 2018. Management was divided into Surgery, Radiotherapy, and Chemotherapy.
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spelling pubmed-90143652022-04-19 Molecular Patho-mechanisms of cervical cancer (MMP1) Kurnia, Iwan Rauf, Syahrul Hatta, Mochammad Arifuddin, Sharvianty Hidayat, Yudi Maulana Natzir, Rosdiana Kaelan, Cahyo Bukhari, Agussalim Pelupessy, Nugraha Utama Patelonggi, Ilham Jaya Ann Med Surg (Lond) Systematic Review / Meta-analysis Cervical cancer mostly caused by Human Papilloma Virus. Staging and therapy have been extensively studied, and highly correlated with the cellular development of oncogenesis. Mutation was caused by E6 and E7 oncoprotein, also inactivation of 2 tumor suppressor factors (pRB and p53). P53 also regulated MMP1, which dysregulation of MMP transcription would promote tumor metastasis, because of its role in extracellular matrix degradation in tumor invasion. Clinical staging of Cervical Cancer was based on Federation International of Gynaecology and Obstetrics (FIGO) classification from 2018. Management was divided into Surgery, Radiotherapy, and Chemotherapy. Elsevier 2022-03-31 /pmc/articles/PMC9014365/ /pubmed/35444805 http://dx.doi.org/10.1016/j.amsu.2022.103415 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review / Meta-analysis
Kurnia, Iwan
Rauf, Syahrul
Hatta, Mochammad
Arifuddin, Sharvianty
Hidayat, Yudi Maulana
Natzir, Rosdiana
Kaelan, Cahyo
Bukhari, Agussalim
Pelupessy, Nugraha Utama
Patelonggi, Ilham Jaya
Molecular Patho-mechanisms of cervical cancer (MMP1)
title Molecular Patho-mechanisms of cervical cancer (MMP1)
title_full Molecular Patho-mechanisms of cervical cancer (MMP1)
title_fullStr Molecular Patho-mechanisms of cervical cancer (MMP1)
title_full_unstemmed Molecular Patho-mechanisms of cervical cancer (MMP1)
title_short Molecular Patho-mechanisms of cervical cancer (MMP1)
title_sort molecular patho-mechanisms of cervical cancer (mmp1)
topic Systematic Review / Meta-analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014365/
https://www.ncbi.nlm.nih.gov/pubmed/35444805
http://dx.doi.org/10.1016/j.amsu.2022.103415
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