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Long-term and potent IOP-lowering effect of IκBα-siRNA in a nonhuman primate model of chronic ocular hypertension
Glaucoma is one of the most common causes of irreversible blindness. It is acknowledged that lowering intraocular pressure (IOP) is the effective treatment to slow glaucoma disease progression. The main obstacle of existing drugs is that the effect of reducing IOP does not last long. Degradation of...
Autores principales: | Sun, Difang, Zhan, Zongyi, Zeng, Rui, Liu, Xiaolin, Wang, Bin, Yang, Fan, Huang, Sa, Li, Yunfeng, Yang, Zhenlan, Su, Yuanyuan, Lan, Yuqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014385/ https://www.ncbi.nlm.nih.gov/pubmed/35445186 http://dx.doi.org/10.1016/j.isci.2022.104149 |
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