Long-term and potent IOP-lowering effect of IκBα-siRNA in a nonhuman primate model of chronic ocular hypertension

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Glaucoma is one of the most common causes of irreversible blindness. It is acknowledged that lowering intraocular pressure (IOP) is the effective treatment to slow glaucoma disease progression. The main obstacle of existing drugs is that the effect of reducing IOP does not last long. Degradation of...

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Detalles Bibliográficos
Autores principales: Sun, Difang, Zhan, Zongyi, Zeng, Rui, Liu, Xiaolin, Wang, Bin, Yang, Fan, Huang, Sa, Li, Yunfeng, Yang, Zhenlan, Su, Yuanyuan, Lan, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014385/
https://www.ncbi.nlm.nih.gov/pubmed/35445186
http://dx.doi.org/10.1016/j.isci.2022.104149
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