Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics

Currently, most CNS tumors require tissue sampling to discern their molecular/genomic landscape. However, growing research has shown the powerful role imaging can play in non-invasively and accurately detecting the molecular signature of these tumors. The overarching theme of this review article is...

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Autores principales: Vagvala, Saivenkat, Guenette, Jeffrey P., Jaimes, Camilo, Huang, Raymond Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014574/
https://www.ncbi.nlm.nih.gov/pubmed/35436952
http://dx.doi.org/10.1186/s40644-022-00455-5
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author Vagvala, Saivenkat
Guenette, Jeffrey P.
Jaimes, Camilo
Huang, Raymond Y.
author_facet Vagvala, Saivenkat
Guenette, Jeffrey P.
Jaimes, Camilo
Huang, Raymond Y.
author_sort Vagvala, Saivenkat
collection PubMed
description Currently, most CNS tumors require tissue sampling to discern their molecular/genomic landscape. However, growing research has shown the powerful role imaging can play in non-invasively and accurately detecting the molecular signature of these tumors. The overarching theme of this review article is to provide neuroradiologists and neurooncologists with a framework of several important molecular markers, their associated imaging features and the accuracy of those features. A particular emphasis is placed on those tumors and mutations that have specific or promising imaging correlates as well as their respective therapeutic potentials.
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spelling pubmed-90145742022-04-19 Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics Vagvala, Saivenkat Guenette, Jeffrey P. Jaimes, Camilo Huang, Raymond Y. Cancer Imaging Review Currently, most CNS tumors require tissue sampling to discern their molecular/genomic landscape. However, growing research has shown the powerful role imaging can play in non-invasively and accurately detecting the molecular signature of these tumors. The overarching theme of this review article is to provide neuroradiologists and neurooncologists with a framework of several important molecular markers, their associated imaging features and the accuracy of those features. A particular emphasis is placed on those tumors and mutations that have specific or promising imaging correlates as well as their respective therapeutic potentials. BioMed Central 2022-04-18 /pmc/articles/PMC9014574/ /pubmed/35436952 http://dx.doi.org/10.1186/s40644-022-00455-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Vagvala, Saivenkat
Guenette, Jeffrey P.
Jaimes, Camilo
Huang, Raymond Y.
Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
title Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
title_full Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
title_fullStr Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
title_full_unstemmed Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
title_short Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
title_sort imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014574/
https://www.ncbi.nlm.nih.gov/pubmed/35436952
http://dx.doi.org/10.1186/s40644-022-00455-5
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