Exosomal miR-301a-3p from esophageal squamous cell carcinoma cells promotes angiogenesis by inducing M2 polarization of macrophages via the PTEN/PI3K/AKT signaling pathway

BACKGROUND: Growing evidence has indicated that tumor-associated macrophages (TAMs) promote tumor angiogenesis. However, the mechanisms underlying the pro-angiogenic switch of TAMs remains unclear. Here, we examined how exosomal miR-301a-3p secreted by esophageal squamous cell carcinoma (ESCC) cells...

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Detalles Bibliográficos
Autores principales: Shou, Yuwei, Wang, Xiaoqian, Chen, Chao, Liang, Yinghao, Yang, Chenbo, Xiao, Qiankun, Li, Hui, Wang, Shuaiyuan, Shu, Jiao, Tian, Xiangyu, Chen, Kuisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014619/
https://www.ncbi.nlm.nih.gov/pubmed/35436935
http://dx.doi.org/10.1186/s12935-022-02570-6

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