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Planning a method for covariate adjustment in individually randomised trials: a practical guide

BACKGROUND: It has long been advised to account for baseline covariates in the analysis of confirmatory randomised trials, with the main statistical justifications being that this increases power and, when a randomisation scheme balanced covariates, permits a valid estimate of experimental error. Th...

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Detalles Bibliográficos
Autores principales:	Morris, Tim P., Walker, A. Sarah, Williamson, Elizabeth J., White, Ian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014627/ https://www.ncbi.nlm.nih.gov/pubmed/35436970 http://dx.doi.org/10.1186/s13063-022-06097-z

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