Combined administration of inhaled DNase, baricitinib and tocilizumab as rescue treatment in COVID-19 patients with severe respiratory failure

Aiming to reduce mortality in COVID-19 with severe respiratory failure we administered a combined rescue treatment (COMBI) on top of standard-of-care (SOC: dexamethasone/heparin) consisted of inhaled DNase to dissolve thrombogenic neutrophil extracellular traps, plus agents against cytokine-mediated...

Descripción completa

Detalles Bibliográficos
Autores principales: Gavriilidis, Efstratios, Antoniadou, Christina, Chrysanthopoulou, Akrivi, Ntinopoulou, Maria, Smyrlis, Andreas, Fotiadou, Iliana, Zioga, Nikoleta, Kogias, Dionysios, Natsi, Anastasia-Maria, Pelekoudas, Christos, Satiridou, Evangelia, Bakola, Stefania-Aspasia, Papagoras, Charalampos, Mitroulis, Ioannis, Peichamperis, Paschalis, Mikroulis, Dimitrios, Papadopoulos, Vasileios, Skendros, Panagiotis, Ritis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014660/
https://www.ncbi.nlm.nih.gov/pubmed/35447311
http://dx.doi.org/10.1016/j.clim.2022.109016

Ejemplares similares

Ejemplares similares