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Assessment of chimeric antigen receptor T cytotoxicity by droplet microfluidics in vitro

Chimeric antigen receptor T (CAR-T) cells are cytotoxic T cells engineered to specifically kill cancer cells expressing specific target receptor(s). Prior CAR-T efficacy tests include CAR expression analysis by qPCR or ELISA, in vitro measurement of interferon-γ (IFNγ) or interleukin-2 (IL-2), and x...

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Detalles Bibliográficos
Autores principales:	Wong, Kuan Un, Shi, Jingxuan, Li, Peng, Wang, Haitao, Jia, Yanwei, Deng, Chuxia, Jiang, Lianmei, Wong, Ada Hang-Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014740/ https://www.ncbi.nlm.nih.gov/pubmed/35441124 http://dx.doi.org/10.1093/abt/tbac008

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