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Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human

Understanding new modulators of axon regeneration is central to neural repair. Our previous work demonstrated critical roles of atypical cadherin Celsr2 during neural development, including cilia organization, neuron migration and axon navigation. Here, we address its role in axon regeneration. We s...

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Detalles Bibliográficos
Autores principales: Wen, Quan, Weng, Huandi, Liu, Tao, Yu, Lingtai, Zhao, Tianyun, Qin, Jingwen, Li, Si, Wu, Qingfeng, Tissir, Fadel, Qu, Yibo, Zhou, Libing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014747/
https://www.ncbi.nlm.nih.gov/pubmed/34983065
http://dx.doi.org/10.1093/brain/awab317