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Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression
Genome-wide association studies have shown that genetic variants at 2q33.1 are strongly associated with schizophrenia. However, potential causal variants in this locus and their roles in schizophrenia remain unknown. Here, we identified two functional variants (rs796364 and rs281759) that disrupt CT...
Autores principales: | Li, Shiwu, Li, Jiao, Liu, Jiewei, Wang, Junyang, Li, Xiaoyan, Huo, Yongxia, Li, Yifan, Liu, Yixing, Li, Ming, Xiao, Xiao, Luo, Xiong-Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014752/ https://www.ncbi.nlm.nih.gov/pubmed/34581804 http://dx.doi.org/10.1093/brain/awab357 |
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