Oppositional poly(A) tail length regulation by FMRP and CPEB1

Poly(A) tail length is regulated in both the nucleus and cytoplasm. One factor that controls polyadenylation in the cytoplasm is CPEB1, an RNA binding protein that associates with specific mRNA 3′UTR sequences to tether enzymes that add and remove poly(A). Two of these enzymes, the noncanonical poly...

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Detalles Bibliográficos
Autores principales: Shin, Jihae, Paek, Ki Young, Chikhaoui, Lies, Jung, Suna, Ponny, SitharaRaju, Suzuki, Yutaka, Padmanabhan, Kiran, Richter, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014880/
https://www.ncbi.nlm.nih.gov/pubmed/35217597
http://dx.doi.org/10.1261/rna.079050.121

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