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Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities

As a renowned local anesthetic agent of choice, lidocaine is also a class 1b antiarrhythmic agent that is primarily used for the treatment of ventricular arrhythmias. Although lidocaine systemic toxicity is rare, it may be life-threatening; thus, its early identification and management are of vital...

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Detalles Bibliográficos
Autores principales: Daraz, Yasmeen M, Abdelghffar, Omar H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015055/
https://www.ncbi.nlm.nih.gov/pubmed/35464548
http://dx.doi.org/10.7759/cureus.23310
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author Daraz, Yasmeen M
Abdelghffar, Omar H
author_facet Daraz, Yasmeen M
Abdelghffar, Omar H
author_sort Daraz, Yasmeen M
collection PubMed
description As a renowned local anesthetic agent of choice, lidocaine is also a class 1b antiarrhythmic agent that is primarily used for the treatment of ventricular arrhythmias. Although lidocaine systemic toxicity is rare, it may be life-threatening; thus, its early identification and management are of vital importance. This case report details the clinical scenario of intravenous lidocaine administration to a patient at high risk of toxicity in a 64-year-old patient, who initially presented with sustained monomorphic ventricular tachycardia received lidocaine and subsequently developed neurologic manifestations of lidocaine toxicity, including altered mental status and seizure. The patient was treated promptly with benzodiazepine and discontinuation of lidocaine as the offending agent, with complete resolution of adverse effects.
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spelling pubmed-90150552022-04-22 Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities Daraz, Yasmeen M Abdelghffar, Omar H Cureus Anesthesiology As a renowned local anesthetic agent of choice, lidocaine is also a class 1b antiarrhythmic agent that is primarily used for the treatment of ventricular arrhythmias. Although lidocaine systemic toxicity is rare, it may be life-threatening; thus, its early identification and management are of vital importance. This case report details the clinical scenario of intravenous lidocaine administration to a patient at high risk of toxicity in a 64-year-old patient, who initially presented with sustained monomorphic ventricular tachycardia received lidocaine and subsequently developed neurologic manifestations of lidocaine toxicity, including altered mental status and seizure. The patient was treated promptly with benzodiazepine and discontinuation of lidocaine as the offending agent, with complete resolution of adverse effects. Cureus 2022-03-19 /pmc/articles/PMC9015055/ /pubmed/35464548 http://dx.doi.org/10.7759/cureus.23310 Text en Copyright © 2022, Daraz et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Anesthesiology
Daraz, Yasmeen M
Abdelghffar, Omar H
Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities
title Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities
title_full Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities
title_fullStr Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities
title_full_unstemmed Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities
title_short Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities
title_sort lidocaine infusion: an antiarrhythmic with neurologic toxicities
topic Anesthesiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015055/
https://www.ncbi.nlm.nih.gov/pubmed/35464548
http://dx.doi.org/10.7759/cureus.23310
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