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D-dimer and CoV-2 spike-immune complexes contribute to the production of PGE2 and proinflammatory cytokines in monocytes

An overreactive inflammatory response and coagulopathy are observed in patients with severe form of COVID-19. Since increased levels of D-dimer (DD) are associated with coagulopathy in COVID-19, we explored whether DD contributes to the aberrant cytokine responses. Here we show that treatment of hea...

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Detalles Bibliográficos
Autores principales:	Park, Yun-Jong, Acosta, David, Vassell, Russell, Tang, Juanjie, Khurana, Surender, Weiss, Carol D., Golding, Hana, Zaitseva, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015149/ https://www.ncbi.nlm.nih.gov/pubmed/35385545 http://dx.doi.org/10.1371/journal.ppat.1010468

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