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Crystal structure of an RNA/DNA strand exchange junction

Short segments of RNA displace one strand of a DNA duplex during diverse processes including transcription and CRISPR-mediated immunity and genome editing. These strand exchange events involve the intersection of two geometrically distinct helix types—an RNA:DNA hybrid (A-form) and a DNA:DNA homodup...

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Detalles Bibliográficos
Autores principales:	Cofsky, Joshua C., Knott, Gavin J., Gee, Christine L., Doudna, Jennifer A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015157/ https://www.ncbi.nlm.nih.gov/pubmed/35436289 http://dx.doi.org/10.1371/journal.pone.0263547

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