Cargando…

Crystal structure of an RNA/DNA strand exchange junction

Short segments of RNA displace one strand of a DNA duplex during diverse processes including transcription and CRISPR-mediated immunity and genome editing. These strand exchange events involve the intersection of two geometrically distinct helix types—an RNA:DNA hybrid (A-form) and a DNA:DNA homodup...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cofsky, Joshua C., Knott, Gavin J., Gee, Christine L., Doudna, Jennifer A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015157/ https://www.ncbi.nlm.nih.gov/pubmed/35436289 http://dx.doi.org/10.1371/journal.pone.0263547

Ejemplares similares

CRISPR-Cas9 bends and twists DNA to read its sequence
por: Cofsky, Joshua C., et al.
Publicado: (2022)

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
por: Cofsky, Joshua C, et al.
Publicado: (2020)

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2
por: Alecki, Célia, et al.
Publicado: (2020)

Structural dynamics of a single-stranded RNA–helix junction using NMR
por: Eichhorn, Catherine D., et al.
Publicado: (2014)

Equilibrious Strand Exchange Promoted by DNA Conformational Switching
por: Wu, Zhiguo, et al.
Publicado: (2013)

Mechanism of strand exchange from RecA-DNA synaptic and D-loop structures
por: Yang, Haijuan, et al.
Publicado: (2020)

Connecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombination
por: Sansam, Christopher L, et al.
Publicado: (2015)

Biochemical characterization of the RNA-binding and RNA–DNA strand exchange activities of the human RAD52 protein
por: Tsuchiya, Ryohei, et al.
Publicado: (2023)

Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA
por: Liu, Yijin, et al.
Publicado: (2017)

Flanking strand separation activity of RecA nucleoprotein filaments in DNA strand exchange reactions
por: Yu, Fangzhi, et al.
Publicado: (2023)

Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
por: Xiao, Botao, et al.
Publicado: (2016)

Control of directionality in the DNA strand-exchange reaction catalysed by the tyrosine recombinase TnpI
por: Vanhooff, Virginie, et al.
Publicado: (2010)

Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE
por: Sen, Doyel, et al.
Publicado: (2016)

ctDNA Detection Based on DNA Clutch Probes and Strand Exchange Mechanism
por: Chang, Huan, et al.
Publicado: (2018)

Cofactor-assisted three-way DNA junction-driven strand displacement
por: Jia, Yufeng, et al.
Publicado: (2021)

DNA recognition by an RNA-guided bacterial Argonaute
por: Doxzen, Kevin W., et al.
Publicado: (2017)

The crystal structure of a replicative hexameric helicase DnaC and its complex with single-stranded DNA
por: Lo, Yu-Hua, et al.
Publicado: (2009)

Role of Order in the Mechanism of Charge Transport across Single-Stranded and Double-Stranded DNA Monolayers in Tunnel Junctions
por: Gupta, Nipun Kumar, et al.
Publicado: (2021)

An archaeal Rad54 protein remodels DNA and stimulates DNA strand exchange by RadA
por: Haseltine, Cynthia A., et al.
Publicado: (2009)

Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA
por: Graham, John S., et al.
Publicado: (2011)

Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage
por: Rychlik, Monika P., et al.
Publicado: (2010)

The Hin recombinase assembles a tetrameric protein swivel that exchanges DNA strands
por: Dhar, Gautam, et al.
Publicado: (2009)

Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells
por: Deveryshetty, Jaigeeth, et al.
Publicado: (2019)

The telomere resolvase of the Lyme disease spirochete, Borrelia burgdorferi, promotes DNA single-strand annealing and strand exchange
por: Mir, Taskia, et al.
Publicado: (2013)

DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae
por: Hum, Yee Fang, et al.
Publicado: (2018)

Reconstitution of DNA Strand Exchange Mediated by Rhp51 Recombinase and Two Mediators
por: Kurokawa, Yumiko, et al.
Publicado: (2008)

Bacillus subtilis DisA regulates RecA-mediated DNA strand exchange
por: Torres, Rubén, et al.
Publicado: (2019)

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity
por: Kouno, Takahide, et al.
Publicado: (2017)

Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition
por: Choi, Sung-Jin, et al.
Publicado: (2016)

Mycobacterium tuberculosis nucleoid-associated DNA-binding protein H-NS binds with high-affinity to the Holliday junction and inhibits strand exchange promoted by RecA protein
por: Sharadamma, N., et al.
Publicado: (2010)

Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork
por: Kanagaraj, Radhakrishnan, et al.
Publicado: (2006)

Crystal Structure of a Nitrate/Nitrite Exchanger
por: Zheng, Hongjin, et al.
Publicado: (2013)

Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
por: Hu, Tianyu, et al.
Publicado: (2021)

Bacillus subtilis MutS Modulates RecA-Mediated DNA Strand Exchange Between Divergent DNA Sequences
por: Carrasco, Begoña, et al.
Publicado: (2019)

Identification of a novel human Rad51 variant that promotes DNA strand exchange
por: Park, Jung-Young, et al.
Publicado: (2008)

RadD is a RecA-dependent accessory protein that accelerates DNA strand exchange
por: Bonde, Nina J, et al.
Publicado: (2022)

Computing in mammalian cells with nucleic acid strand exchange
por: Groves, Benjamin, et al.
Publicado: (2015)

Circular Single-Stranded Synthetic DNA Delivery Vectors for MicroRNA
por: Seidl, Christine I., et al.
Publicado: (2011)

The Sense and Sensibility of Strand Exchange in Recombination Homeostasis
por: Cole, Francesca
Publicado: (2014)

Racemic crystal structures of A-DNA duplexes
por: Mandal, Pradeep K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l84d5gam0b3kcfa3bitcqs7hl6