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Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination
Sera of vaccines were assessed by surrogate virus neutralization tests for their capacity to neutralize the SARS‐CoV‐2 Delta variant. Homologous prime‐boost immunization with Moderna's Spikevax as well as heterologous immunization with AstraZeneca's Vaxzevria followed by Moderna's Spi...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015245/ https://www.ncbi.nlm.nih.gov/pubmed/34870322 http://dx.doi.org/10.1002/eji.202149645 |
| _version_ | 1784688343383015424 |
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| author | Hammerschmidt, Swantje I. Thurm, Christoph Bošnjak, Berislav Bernhardt, Günter Reinhold, Annegret Willenzon, Stefanie Ritter, Christiane Reinhold, Dirk Schraven, Burkhart Förster, Reinhold |
| author_facet | Hammerschmidt, Swantje I. Thurm, Christoph Bošnjak, Berislav Bernhardt, Günter Reinhold, Annegret Willenzon, Stefanie Ritter, Christiane Reinhold, Dirk Schraven, Burkhart Förster, Reinhold |
| author_sort | Hammerschmidt, Swantje I. |
| collection | PubMed |
| description | Sera of vaccines were assessed by surrogate virus neutralization tests for their capacity to neutralize the SARS‐CoV‐2 Delta variant. Homologous prime‐boost immunization with Moderna's Spikevax as well as heterologous immunization with AstraZeneca's Vaxzevria followed by Moderna's Spikevax were identified as highly potent vaccination regimens for the induction of Delta‐neutralizing antibodies. [Image: see text] |
| format | Online Article Text |
| id | pubmed-9015245 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-90152452022-04-19 Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination Hammerschmidt, Swantje I. Thurm, Christoph Bošnjak, Berislav Bernhardt, Günter Reinhold, Annegret Willenzon, Stefanie Ritter, Christiane Reinhold, Dirk Schraven, Burkhart Förster, Reinhold Eur J Immunol Notes and Insights Sera of vaccines were assessed by surrogate virus neutralization tests for their capacity to neutralize the SARS‐CoV‐2 Delta variant. Homologous prime‐boost immunization with Moderna's Spikevax as well as heterologous immunization with AstraZeneca's Vaxzevria followed by Moderna's Spikevax were identified as highly potent vaccination regimens for the induction of Delta‐neutralizing antibodies. [Image: see text] John Wiley and Sons Inc. 2022-01-07 2022-02 /pmc/articles/PMC9015245/ /pubmed/34870322 http://dx.doi.org/10.1002/eji.202149645 Text en © 2022 The Authors. European Journal of Immunology published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | Notes and Insights Hammerschmidt, Swantje I. Thurm, Christoph Bošnjak, Berislav Bernhardt, Günter Reinhold, Annegret Willenzon, Stefanie Ritter, Christiane Reinhold, Dirk Schraven, Burkhart Förster, Reinhold Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination |
| title | Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination |
| title_full | Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination |
| title_fullStr | Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination |
| title_full_unstemmed | Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination |
| title_short | Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination |
| title_sort | robust induction of neutralizing antibodies against the sars‐cov‐2 delta variant after homologous spikevax or heterologous vaxzevria‐spikevax vaccination |
| topic | Notes and Insights |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015245/ https://www.ncbi.nlm.nih.gov/pubmed/34870322 http://dx.doi.org/10.1002/eji.202149645 |
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