A Universal DNA Aptamer that Recognizes Spike Proteins of Diverse SARS‐CoV‐2 Variants of Concern

We report on a unique DNA aptamer, denoted MSA52, that displays universally high affinity for the spike proteins of wildtype SARS‐CoV‐2 as well as the Alpha, Beta, Gamma, Epsilon, Kappa, Delta and Omicron variants. Using an aptamer pool produced from round 13 of selection against the S1 domain of th...

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Detalles Bibliográficos
Autores principales: Zhang, Zijie, Li, Jiuxing, Gu, Jimmy, Amini, Ryan, Stacey, Hannah D., Ang, Jann C., White, Dawn, Filipe, Carlos D. M., Mossman, Karen, Miller, Matthew S., Salena, Bruno J., Yamamura, Deborah, Sen, Payel, Soleymani, Leyla, Brennan, John D., Li, Yingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015322/
https://www.ncbi.nlm.nih.gov/pubmed/35084794
http://dx.doi.org/10.1002/chem.202200078

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