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AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection
A late presenter AIDS patient with severe T cell depletion presented non‐severe COVID‐19 symptoms, with prolonged viral shedding. Our case report supports the hypothesis that an effective T cell response may be dispensable for the control of COVID‐19 progression to severe forms, while it may be nece...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015404/ https://www.ncbi.nlm.nih.gov/pubmed/34822185 http://dx.doi.org/10.1002/eji.202149574 |
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| author | Spinicci, Michele Mazzoni, Alessio Borchi, Beatrice Graziani, Lucia Mazzetti, Marcello Bartalesi, Filippo Botta, Annarita Tilli, Marta Pieralli, Filippo Coppi, Marco Giovacchini, Nicla Colao, Maria Grazia Saccardi, Riccardo Rossolini, Gian Maria Annunziato, Francesco Bartoloni, Alessandro |
| author_facet | Spinicci, Michele Mazzoni, Alessio Borchi, Beatrice Graziani, Lucia Mazzetti, Marcello Bartalesi, Filippo Botta, Annarita Tilli, Marta Pieralli, Filippo Coppi, Marco Giovacchini, Nicla Colao, Maria Grazia Saccardi, Riccardo Rossolini, Gian Maria Annunziato, Francesco Bartoloni, Alessandro |
| author_sort | Spinicci, Michele |
| collection | PubMed |
| description | A late presenter AIDS patient with severe T cell depletion presented non‐severe COVID‐19 symptoms, with prolonged viral shedding. Our case report supports the hypothesis that an effective T cell response may be dispensable for the control of COVID‐19 progression to severe forms, while it may be necessary for SARS‐CoV‐2 clearance. [Image: see text] |
| format | Online Article Text |
| id | pubmed-9015404 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-90154042022-04-19 AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection Spinicci, Michele Mazzoni, Alessio Borchi, Beatrice Graziani, Lucia Mazzetti, Marcello Bartalesi, Filippo Botta, Annarita Tilli, Marta Pieralli, Filippo Coppi, Marco Giovacchini, Nicla Colao, Maria Grazia Saccardi, Riccardo Rossolini, Gian Maria Annunziato, Francesco Bartoloni, Alessandro Eur J Immunol Notes and Insights A late presenter AIDS patient with severe T cell depletion presented non‐severe COVID‐19 symptoms, with prolonged viral shedding. Our case report supports the hypothesis that an effective T cell response may be dispensable for the control of COVID‐19 progression to severe forms, while it may be necessary for SARS‐CoV‐2 clearance. [Image: see text] John Wiley and Sons Inc. 2021-12-04 2022-02 /pmc/articles/PMC9015404/ /pubmed/34822185 http://dx.doi.org/10.1002/eji.202149574 Text en © 2021 The Authors. European Journal of Immunology published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Notes and Insights Spinicci, Michele Mazzoni, Alessio Borchi, Beatrice Graziani, Lucia Mazzetti, Marcello Bartalesi, Filippo Botta, Annarita Tilli, Marta Pieralli, Filippo Coppi, Marco Giovacchini, Nicla Colao, Maria Grazia Saccardi, Riccardo Rossolini, Gian Maria Annunziato, Francesco Bartoloni, Alessandro AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection |
| title | AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection |
| title_full | AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection |
| title_fullStr | AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection |
| title_full_unstemmed | AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection |
| title_short | AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection |
| title_sort | aids patient with severe t cell depletion achieved control but not clearance of sars‐cov‐2 infection |
| topic | Notes and Insights |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015404/ https://www.ncbi.nlm.nih.gov/pubmed/34822185 http://dx.doi.org/10.1002/eji.202149574 |
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