Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant

A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with severe acute respiratory syndrome coronavirus 2 as evidenced by clinical presentation, neuroimaging, and cerebrospinal fluid studies. Our patient was treated with high-dose intravenous methylpredniso...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Mariha, Bhattarai, Samhita, Boyce, Thomas G., Hayek, Reyaad A., Zhadanov, Sergey I., Hooper, Elisabeth E., Fernandez, Edward G., Koehn, Monica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015721/
https://www.ncbi.nlm.nih.gov/pubmed/35447125
http://dx.doi.org/10.1016/j.jpeds.2022.04.031
_version_ 1784688371926302720
author Khan, Mariha
Bhattarai, Samhita
Boyce, Thomas G.
Hayek, Reyaad A.
Zhadanov, Sergey I.
Hooper, Elisabeth E.
Fernandez, Edward G.
Koehn, Monica A.
author_facet Khan, Mariha
Bhattarai, Samhita
Boyce, Thomas G.
Hayek, Reyaad A.
Zhadanov, Sergey I.
Hooper, Elisabeth E.
Fernandez, Edward G.
Koehn, Monica A.
author_sort Khan, Mariha
collection PubMed
description A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with severe acute respiratory syndrome coronavirus 2 as evidenced by clinical presentation, neuroimaging, and cerebrospinal fluid studies. Our patient was treated with high-dose intravenous methylprednisolone, tocilizumab, and intravenous immunoglobulin with significant short-term clinical improvement but long-term sequelae.
format Online
Article
Text
id pubmed-9015721
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-90157212022-04-19 Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant Khan, Mariha Bhattarai, Samhita Boyce, Thomas G. Hayek, Reyaad A. Zhadanov, Sergey I. Hooper, Elisabeth E. Fernandez, Edward G. Koehn, Monica A. J Pediatr Brief Reports A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with severe acute respiratory syndrome coronavirus 2 as evidenced by clinical presentation, neuroimaging, and cerebrospinal fluid studies. Our patient was treated with high-dose intravenous methylprednisolone, tocilizumab, and intravenous immunoglobulin with significant short-term clinical improvement but long-term sequelae. Elsevier Inc. 2022-08 2022-04-18 /pmc/articles/PMC9015721/ /pubmed/35447125 http://dx.doi.org/10.1016/j.jpeds.2022.04.031 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Reports
Khan, Mariha
Bhattarai, Samhita
Boyce, Thomas G.
Hayek, Reyaad A.
Zhadanov, Sergey I.
Hooper, Elisabeth E.
Fernandez, Edward G.
Koehn, Monica A.
Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
title Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
title_full Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
title_fullStr Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
title_full_unstemmed Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
title_short Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant
title_sort acute necrotizing encephalopathy associated with coronavirus disease 2019 in an infant
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015721/
https://www.ncbi.nlm.nih.gov/pubmed/35447125
http://dx.doi.org/10.1016/j.jpeds.2022.04.031
work_keys_str_mv AT khanmariha acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant
AT bhattaraisamhita acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant
AT boycethomasg acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant
AT hayekreyaada acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant
AT zhadanovsergeyi acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant
AT hooperelisabethe acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant
AT fernandezedwardg acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant
AT koehnmonicaa acutenecrotizingencephalopathyassociatedwithcoronavirusdisease2019inaninfant

Ejemplares similares