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The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke

OBJECTIVE: The objective of this study was to evaluate how COVID-19 affects patients with acute ischemic or hemorrhagic stroke outcome. MATERIALS AND METHODS: This retrospective study was performed on adult patients (> 18 years old) with stroke (ischemic or hemorrhagic) who were admitted to hospi...

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Autores principales: Amiri, Hesamodin Ashrafian, Razavi, Athena Sharifi, Tabrizi, Nasim, Cheraghmakani, Hamed, Baghbanian, Seyed Mohammad, Sedaghat-Chaijan, Mehraz, Zarvani, Ashraf, Ghazaeian, Monireh, Hosseinnataj, Abolfazl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015955/
https://www.ncbi.nlm.nih.gov/pubmed/35489184
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106512
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author Amiri, Hesamodin Ashrafian
Razavi, Athena Sharifi
Tabrizi, Nasim
Cheraghmakani, Hamed
Baghbanian, Seyed Mohammad
Sedaghat-Chaijan, Mehraz
Zarvani, Ashraf
Ghazaeian, Monireh
Hosseinnataj, Abolfazl
author_facet Amiri, Hesamodin Ashrafian
Razavi, Athena Sharifi
Tabrizi, Nasim
Cheraghmakani, Hamed
Baghbanian, Seyed Mohammad
Sedaghat-Chaijan, Mehraz
Zarvani, Ashraf
Ghazaeian, Monireh
Hosseinnataj, Abolfazl
author_sort Amiri, Hesamodin Ashrafian
collection PubMed
description OBJECTIVE: The objective of this study was to evaluate how COVID-19 affects patients with acute ischemic or hemorrhagic stroke outcome. MATERIALS AND METHODS: This retrospective study was performed on adult patients (> 18 years old) with stroke (ischemic or hemorrhagic) who were admitted to hospital with or without COVID-19. The primary outcome was stroke-related disability, which was measured by mRS at baseline and discharge. Hospital duration, intensive care unit (ICU) admission, and mortality were considered the secondary outcomes. RESULTS: From February 2019 until August 2020, we recruited and analyzed 151 patients, 42 of whom had COVID-19 based on RT-PCR tests or lung CT scan findings. COVID-19 positive patients had higher baseline and final mRS scores than the control group (4.46 ± 0.67 vs 4.79 ± 0.61, P: 0.001, 3.83 ± 1.22 vs 4.46 ± 0.67, P: 0.001). Moreover, stroke patients with COVID-19 experienced a more severe disease and required a higher rate of ICU admission (17 vs 0, P:0.001) and longer hospitalization compared to those without COVID-19 (8.50 ± 7.86 vs 7.5 ± 11.20, P: 0.021). Also, mortality was higher in the COVID-19 group (19 vs 13, P:0.001). There was not any significant differences between the two groups in terms of the involvement of cerebral arteries and type of stroke. Male sex, COVID-19, and ICU admission were the main independent risk factors for death. CONCLUSION: The results of the study showed stroke patients (ischemic or hemorrhagic) with COVID-19 can have more disabilities and incur more hospital complications and mortality than non-COVID-19 patients.
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spelling pubmed-90159552022-04-19 The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke Amiri, Hesamodin Ashrafian Razavi, Athena Sharifi Tabrizi, Nasim Cheraghmakani, Hamed Baghbanian, Seyed Mohammad Sedaghat-Chaijan, Mehraz Zarvani, Ashraf Ghazaeian, Monireh Hosseinnataj, Abolfazl J Stroke Cerebrovasc Dis Article OBJECTIVE: The objective of this study was to evaluate how COVID-19 affects patients with acute ischemic or hemorrhagic stroke outcome. MATERIALS AND METHODS: This retrospective study was performed on adult patients (> 18 years old) with stroke (ischemic or hemorrhagic) who were admitted to hospital with or without COVID-19. The primary outcome was stroke-related disability, which was measured by mRS at baseline and discharge. Hospital duration, intensive care unit (ICU) admission, and mortality were considered the secondary outcomes. RESULTS: From February 2019 until August 2020, we recruited and analyzed 151 patients, 42 of whom had COVID-19 based on RT-PCR tests or lung CT scan findings. COVID-19 positive patients had higher baseline and final mRS scores than the control group (4.46 ± 0.67 vs 4.79 ± 0.61, P: 0.001, 3.83 ± 1.22 vs 4.46 ± 0.67, P: 0.001). Moreover, stroke patients with COVID-19 experienced a more severe disease and required a higher rate of ICU admission (17 vs 0, P:0.001) and longer hospitalization compared to those without COVID-19 (8.50 ± 7.86 vs 7.5 ± 11.20, P: 0.021). Also, mortality was higher in the COVID-19 group (19 vs 13, P:0.001). There was not any significant differences between the two groups in terms of the involvement of cerebral arteries and type of stroke. Male sex, COVID-19, and ICU admission were the main independent risk factors for death. CONCLUSION: The results of the study showed stroke patients (ischemic or hemorrhagic) with COVID-19 can have more disabilities and incur more hospital complications and mortality than non-COVID-19 patients. Elsevier Inc. 2022-07 2022-04-19 /pmc/articles/PMC9015955/ /pubmed/35489184 http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106512 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Amiri, Hesamodin Ashrafian
Razavi, Athena Sharifi
Tabrizi, Nasim
Cheraghmakani, Hamed
Baghbanian, Seyed Mohammad
Sedaghat-Chaijan, Mehraz
Zarvani, Ashraf
Ghazaeian, Monireh
Hosseinnataj, Abolfazl
The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke
title The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke
title_full The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke
title_fullStr The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke
title_full_unstemmed The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke
title_short The Effects of COVID-19 on Patients with Acute Ischemic and Hemorrhagic Stroke
title_sort effects of covid-19 on patients with acute ischemic and hemorrhagic stroke
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015955/
https://www.ncbi.nlm.nih.gov/pubmed/35489184
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106512
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