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GSK-126 Protects CA1 Neurons from H3K27me3-Mediated Apoptosis in Cerebral Ischemia

Epigenetics, including histone modifications, play a significant role in central nervous system diseases, but the underlying mechanism remains to be elucidated. The aim of this study was to evaluate the role of H3K27me3 in regulating transcriptomic and pathogenic mechanisms following global ischemic...

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Detalles Bibliográficos
Autores principales: Wang, Zhongcheng, Su, Yaxin, Zhang, Lei, Lan, Ting, Li, Li, Qi, Suhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016005/
https://www.ncbi.nlm.nih.gov/pubmed/35091962
http://dx.doi.org/10.1007/s12035-021-02677-3