Ginsenoside Rg1 Reduced Microglial Activation and Mitochondrial Dysfunction to Alleviate Depression-Like Behaviour Via the GAS5/EZH2/SOCS3/NRF2 Axis

Ginsenoside Rg1 is the principal active ingredient in ginseng. The antidepressant effects of Rg1 have been validated; however, the specific underlying mechanism of this effect needs further research. Rats were subjected to the chronic restraint stress (CRS) depression model. Rg1, or a positive contr...

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Detalles Bibliográficos
Autores principales: Li, Junnan, Gao, Wei, Zhao, Zhonghui, Li, Yannan, Yang, Lixuan, Wei, Wei, Ren, Feifei, Li, Yang, Yu, Yao, Duan, Wenzhe, Li, Jingchun, Dai, Baoan, Guo, Rongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016007/
https://www.ncbi.nlm.nih.gov/pubmed/35230663
http://dx.doi.org/10.1007/s12035-022-02740-7

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