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Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway

We have previously shown that the heteromer composed by the dopamine D3 receptor (D3R) and the nicotinic acetylcholine receptor (nAChR) (D3R-nAChR heteromer) is expressed in dopaminergic neurons, activated by nicotine and represents the molecular unit that, in these neurons, contributes to the modul...

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Detalles Bibliográficos
Autores principales: Mutti, Veronica, Bono, Federica, Tomasoni, Zaira, Bontempi, Leonardo, Guglielmi, Adele, Bolognin, Silvia, Schwamborn, Jens C., Missale, Cristina, Fiorentini, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016044/
https://www.ncbi.nlm.nih.gov/pubmed/35044626
http://dx.doi.org/10.1007/s12035-022-02748-z